Everything about Beta-2 Adrenergic Receptor totally explained
) depicted as a green cartoon structure and the bound partial inverse agonist
carazolol ligand as spheres (carbon atom = grey, oxygen = red, nitrogen = blue). The
phospholipid bilayer is depicted as blue spheres (phosphate head groups) and yellow lines (lipid sidechains).
| PDB =
| Name = Adrenergic, beta-2-, receptor, surface
| HGNCid = 286
| Symbol = ADRB2
| AltSymbols =; ADRB2R; ADRBR; B2AR; BAR; BETA2AR
| OMIM = 109690
| ECnumber =
| Homologene = 30948
| MGIid = 87938
| GeneAtlas_image1 = PBB_GE_ADRB2_206170_at_tn.png
| Function =
| Component =
| Process =
| Orthologs =
}}
The
beta-2 adrenergic receptor (β
2 adrenoreceptor), also known as
ADRB2, is an
beta-adrenergic receptor, and also denotes the human
gene encoding it.
Gene
The gene is
intronless. Different polymorphic forms,
point mutations, and/or
downregulation of this gene are associated with nocturnal
asthma,
obesity and
type 2 diabetes.
Structure
The 3D crystallographic structure (see figure to the right) of the β
2-adrenergic receptor has been determined ( ).
Function
Actions of the β
2 receptor include:
Muscular system
Further Information
Get more info on 'Beta-2 Adrenergic Receptor'.
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